Human bromodomain CREB binding protein (CREBBP), also known as CBP, RSTS and KAT3A, GenBank Accession No. NM_004380, a.a. 1081-1197 corresponding to single bromodomain with N-terminal GST-tag, MW=41 kDa, expressed in an E. coli expression system.
Immunogen Region
1081-1197
Tag
N-terminal GST-tag
Formulation
40 mM Tris-HCl pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20 and 20% glycerol.
Species
Human
Application
Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.
Notes
Assay wasperformed using the BiohippoCREBBP Inhibitor Screening Assay Kit(Catalog #32607) following themanufacturer's instructions.
Avoid freeze/thaw cycles.
GenBank
NM_004380
Mw(kda)
41 kDa
Synonyms
CREBBP, CREB binding protein, CBP, RSTS, KAT3A
Uniprot
Q92793
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Panagopoulos, I., et al., Hum Mol Genet. 2001 Feb 15;10(4): 395-404 2. Huang, W.C., et al., Mol Cell. 2007 Apr 13; 26(1):75-87