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Home / Proteins & Peptide

Ck beta 8?1/CCL23, Human

SKU : BHP18500385

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Mfr.No.	IX03237, IX03237-1, IX03237-10, IX03237-50
Reconstitution	Reconstituted in ddH2O or PBS at 100 ug/ml.
Description	Chemokine (C-C motif) ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family that is also known as Macrophage inflammatory protein 3 (MIP-3) and Myeloid progenitor inhibitory factor 1 (MPIF-1). CCL23 is predominantly expressed in lung and liver tissue, but is also found in bone marrow and placenta.CCL23 is highly chemotactic for resting T cells and monocytes and slightly chemotactic for neutrophils. It has also been attributed to an inhibitory activity on hematopoietic progenitor cells. CCL23 is a ligand for the chemokine receptor CCR1.Recombinant human Ck beta 8?1/CCL23 produced in CHO cells is a single polypeptide chain containing 92 amino acids. A fully biologically active molecule, rhCk beta 8?1/CCL23 has a molecular mass of 10.5 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
Formulation	Lyophilized after extensive dialysis against PBS.
Molecular Weight	10.5 kDa, observed by reducing SDS-PAGE.
Source	CHO
Host	Human
Accession Number	AAC63327
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	The EC50 value of human Ck beta 8?1/CCL23 on Ca2+ mobilization assay in CHO-K1/Ga15/hCCR1 cells (human Ga15 and human CCR1 stably expressed in CHO-K1 cells) is less than 0.4 ug/ml.

Synonyms	Ckbeta 8?1/CCL23, Human
Sequence	MLWRRKIGPQ MTLSHAAGFH ATSADCCISY TPRSIPCSLLESYFETNSEC SKPGVIFLTK KGRRFCANPS DKQVQVCVRMLKLDTRIKTR KN

Purity	98% as analyzed by SDS-PAGE.
Storage	Lyophilized recombinant human Ck beta 8?1/CCL23 remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, human Ck beta 8?1/CCL23 should be stable up to 1 week at 4°C or up to 2 months at -20°C.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500385-1	IX03237-1	1mg	$1373		Add to Cart
BHP18500385-2	IX03237-10	10ug	$74		Add to Cart
BHP18500385-3	IX03237-50	50ug	$199		Add to Cart

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