Human Bromodomain CECR2 (cat eye syndrome chromosome region, candidate 2), GenBank Accession No. NM_031413, a.a. 430-543 corresponding to single bromodomain with N-terminal GST-tag, MW = 40.3 kDa, expressed in an E. coli cell expression system.
Background
CECR2 is a bromodomain-containing protein that is part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with RPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis
Immunogen Region
430-543
Tag
N-terminal GST-tag
Formulation
40 mM Tris-HCl, pH 8, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, and 20% glycerol.
Species
Human
Application
Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.