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Home / Proteins & Peptide

CDK4(EE,T172A)/Cyclin D1, His-tag

SKU : BHP18200168

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BPS Bioscience

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Mfr.No.	40094
Description	Complex of recombinant, full length human CDK4 (GenBank accession number NM_000075) with C-terminal His-tag and modifications (a.a. 43G-47G were replaced with EE, and T172A), and human Cyclin D1 (GenBank accession number NM_053056), a.a. 16-271, were co-expressed in a baculovirus-infected Sf9 cells expression system. CDK4 MW=34 kDa, Cyclin D1 MW=29 kDa. host species: Sf9 cells Host species: Sf9 cells
Immunogen Region	full length
Tag	C-terminal His-tag (CDK4), no tag on Cyclin D1
Formulation	40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.05% Tween-20, 20% glycerol, and 3 mM DTT.
Species	Human
Application	Useful for three dimensional structure studies and binding assays.
Notes	Avoid freeze/thaw cycles.
GenBank	NM_000075(CDK4), NM_053056(cyclin D1)
Mw(kda)	63 kDa (complex)

Synonyms	Cyclin-Dependent Kinase 4, Cell Devision Kinase 4, CDK4, Cyclin D1, CCD1, Bcl1, PRAD1, CCND1
Uniprot	P11802 (CDK4), P24385 (cyclin D1)

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Amendola D. et al., Cell Prolif. 2009. Feb; 42(1):94-109. 2. Yang L. et al., Biochem Cell Biol. 2009. Dec; 87(6):933-42.Application Reference(s): 1. Iterative conversion of cyclin binding groove peptides into druglike CDK inhibitors with antitumor activity (2015)

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200168	40094	20 ug	$390.50		Add to Cart

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