Human CD44, also known as epican, extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, or phagocytic glyco-protein I (PGP-1), GenBank Accession No. NM_000610, a.a. 21-220, fused with Fc region of human IgG, expressed in a HEK293 cell expression system. MW = 48.7 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Species
Human
Application
Useful for studying protein binding and for screening small molecules and antibodies.
Endotoxin Level
<1 EU/ug
Notes
The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_000610
Mw(kda)
48.7 kDa
Synonyms
epican, extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, phagocytic glyco-protein I (PGP-1), homing cell adhesion molecule (HCAM)
Uniprot
P16070
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Prince, M.E., et al., Proc. Natl. Acad. Sci. (USA). 2006; 104(3): 973-978. 2. Lei, D., et al., Clin. Canc. Res. 2008; 14: 6751-6760.