Human secreted CD44, also known as epican, extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, or phagocytic glycoprotein I (PGP-1), GenBank Accession No. NM_000610, a.a. 21-220 expressed in a HEK293 cell expression system, fused at the C-terminus to the Fc portion of human IgG1, and enzymatically biotin-labeled using Avi-tag technology. MW = 50.6 kDa (monomer). This protein runs at a higher M.W. by SDS-PAGE due to glycosylation.
Immunogen Region
21-220
Tag
Fc fusion (Human IgG1), Biotin-labeled
Formulation
8 mM Na Phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol.
Species
Human
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes
HiP indicates a high purity protein with>=90% purity as measured by gel filtration. Avoid freeze/thaw cycles.
GenBank
NM_000610
Mw(kda)
50.6 kDa
Synonyms
epican, extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, phagocytic glyco-protein I (PGP-1), homing cell adhesion molecule (HCAM)
Uniprot
P16070
Shipping Temperature
-80°C (dry ice)
Storage
At least 6 months at -80°C.
Reference
1. Aruffo, A., et al., Cell. 1990; 61(7): 1303-1313. 2. Screaton, G.R., et al., Proc. Natl. Acad. Sci. (USA). 1992; 89(24): 12160-12164.