Human secreted CD27, Fc fusion protein, also known as Tumor Necrosis Factor Receptor Superfamily Member 7, TNFRSF7, and T14, GenBank Accession No. NM_001242, a.a. 21-192 expressed in a HEK293 cell expression system. MW = 45.8 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Immunogen Region
21-192
Tag
C-terminal Fc fusion (Human IgG1)
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Species
Human
Application
Useful for studying protein binding and screening small molecular inhibitors
Endotoxin Level
<1 EU/ug
Notes
The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_001242
Mw(kda)
45.8 kDa
Synonyms
Tumor Necrosis Factor Receptor Superfamily Member 7, TNFRSF7, T14
Uniprot
P26842
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution.
Storage
At least 6 months at -80°C.
Reference
1. Hendricks, J. et al., Nat. Immunol. 2000; 1: 433-440.2. Ruprecht, C.R. et al., J. Exp. Med. 2005; 201(11): 1793-1803.