Human CD244, Fc fusion protein, also known as Natural Killer Cell Receptor 2B4. GenBank Accession No. NM_016382, a.a. 22-229 expressed in a HEK293 cell expression system. This protein is fused at the C-terminus to the Fc region of human IgG1 and is enzymatically biotinylated using Avi-tag technology. MW = 52 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Immunogen Region
22-229
Tag
C-terminal Avi-tag
Formulation
8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Species
Human
Application
Useful for studying protein binding and for screening small molecules and antibodies.
Notes
This protein runs at a higher MW by SDS-PAGE due to glycosylation. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_016382
Mw(kda)
52 kDa+glycans
Synonyms
Natural Killer Cell Receptor 2B4
Uniprot
Q9BZW8
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C. Avoid freeze/thaw cycles. Protein may be diluted to>= 100 ug/ml in PBS + glycerol and stored at -80°C.
Reference
1. Eissmann, P. et al., Blood. 2004; 105: 4722-4729.2. Watzl, C. et al., Journal of Immunology. 2000; 165(7): 3545-3548.