Human secreted CD112, also known as Nectin-2, Herpes virus entry mediator B, HVEB, PVRL2, and PRR2, GenBank Accession No. NM_002856, a.a. 32-360 with a C-terminal His-tag, expressed in a HEK293 cell expression system. MW = 36.4 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Immunogen Region
32-360
Tag
C-terminal His-tag
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
Species
Human
Application
Useful for studying protein binding and screening small molecular inhibitors
Notes
This protein runs at ahigher MW by SDS-PAGE due toglycosylation. The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_002856
Mw(kda)
36.4 kDa + glycans
Synonyms
Nectin-2, Herpes virus entry mediator B, HVEB, PVRL2, and PRR2
Uniprot
Q92692
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Bottino, C., et al., J. Exp. Med. 2003; 198(4): 557-567. 2. Pende, D., et al., Blood. 2005; 105(5): 2066-2073.