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Home / Proteins & Peptide

CBX2, GST-tag

SKU : BHP18200482

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Mfr.No.	55011
Description	Human chromobox homolog 2 (CBX2), also known as SRXY5 and cell division cycle associated 6 (CDCA6), GenBank Accession No. NM_005189, a.a. 2-90, with N-terminal GST-tag, MW=37.3 kDa, expressed in an E. coli cell expression system.
Background	Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys119, rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression.
Immunogen Region	2-90
Tag	N-terminal GST-tag
Formulation	40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM glutathione, 20% glycerol.
Species	Human
Application	Useful for protein binding assays, screening inhibitors, and selectivity profiling.
Notes	Avoid freeze/thaw cycles.
GenBank	NM_005189
Mw(kda)	37.3 kDa

Synonyms	chromobox homolog 2,CBX2, SRXY5, cell division cycle associated 6, CDCA6
Uniprot	Q14781

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Voelkel, P., et al., Epigenetics. 2012 May ;7(5) :482-91. 2. Morey, L., et al., Cell Stem Cell. 2012 Jan 6 ;10(1) :47-62.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200482	55011	100 ug	$506		Add to Cart

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