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Home / Proteins & Peptide

Caspase7, His-tag

SKU : BHP18201518

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BPS Bioscience

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Mfr.No.	70000-1
Description	Human Caspase-7 (full length) (GenBank Accession No. NM_001227) with C-terminal His-tag, MW= 35.1 kDa, expressed in an E. coli expression system. Active caspase 7 is a heterotetramer consisting of two copies each of ~20 kDa and ~11 kDa subunits. Specific activity: >= 5337 pmol/min/ug
Background	Caspase-7 is a member of the caspase (cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis.
Immunogen Region	full length
Tag	C-terminal His-tag
Formulation	40 mM Tris-HCl, pH 8.0,110 mM NaCl, 2.2 mM KCl, 155 mMimidazole, 20% glycerol and 3 mM DTT.
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	Assayed using BPS's Homogeneous Caspase-7 Assay Kit, Cat. # 80701. 10 mM HEPES, pH 7.4, 10 mMEDTA, 0.05% Chaps, 5 mM DTT, and 10uM Caspase substrate. Incubate for 30min at RT. Fluorescence intensitymeasured at exc380/em500 nm Avoid freeze/thaw cycles.
GenBank	NM_001227
Mw(kda)	35.1 kDa

Synonyms	Caspase-7, CASP7, Caspase 7, Mch3, ICE-LAP3
Uniprot	P55210

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	Wang DH., et al., PLoS one,7(6):e39920. doi:10.1371/journal.0039920. (2012).

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18201518	70000-1	10 ug	$313.50		Add to Cart

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