JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Proteins & Peptide

BCL-2, His-tag

SKU : BHP18200369

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

BPS Bioscience

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	50272
Description	Human Bcl-2 (GenBank Accession No. P10415), a.a. 1-211 with C-terminal His-tag, MW = 27 kDa, expressed in an E. coli expression system. Host cell line: E. coli
Background	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Immunogen Region	1-211
Tag	C-terminal His-tag
Formulation	40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 200 mM imidazole
Species	Human
Application	Useful for the study of apoptosis, screening inhibitors, and selectivity profiling.
Notes	Following theprotocol for BPS Cat. #50222. Briefly,BCL-2 was combined with BCL-2peptide ligand in TR-FRET assay bufferalong with anti-His Tb donor and dyelabeledacceptor. Varying concentrationsof ABT 199 were added and the reactionwas incubated at room temperature for 2hours followed by fluorescent intensitymeasurements. Avoid freeze/thaw cycles.
GenBank	P10415
Mw(kda)	27 kDa

Synonyms	Bcl, Bcl2, B cell lymphoma 2
Uniprot	P10415

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Labi V. et al., Cell Death Differ. 2008 Jun;15(6):977-87. 2. Rong Y.P. et al., Mol Cell. 2008 Jul 25;31(2):255-65.

Product Manual	Datasheet

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHP18200369	50272	100 ug	$495		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.