Human BACE1, also known as beta-site amyloid precursor protein cleaving enzyme 1 and ASP2, GenBank Accession No. NM_012104.4, a.a. 22-460, with C-terminal His-Tag, MW=50 kDa, expressed in HEK293 cells.
Immunogen Region
22-460
Tag
C-terminal His-Tag
Formulation
40 mM phosphate buffer, pH 7.4, NaCl 0.110 M, KCl 0.0022 M, 20% glycerol
Species
Human
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes
Avoid freeze/thaw cycles.
GenBank
NM_012104.4
Mw(kda)
50 kDa
Synonyms
beta-site amyloid precursor protein cleaving enzyme 1, ASP2
Uniprot
P56817
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C. Avoid freeze/thaw cycles. Protein may be diluted to>= 100 ug/ml in PBS + glycerol and stored at -80°C.
Reference
1. Luo, Y., et al., Neuroscience. 2001 4; 231-232.2. Cai, H., et al., Neuroscience. 2001 4; 233-234.