Human secreted B7-H5, Fc fusion protein, also known as Gi24, Dies1, VISTA, and SISP1, GenBank Accession No. NM_022153, a.a. 33-194 expressed in a HEK293 cell expression system. MW = 46.7 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Immunogen Region
33-194
Tag
C-terminal Fc fusion (Human IgG1)
Formulation
40 mM Tris, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Species
Human
Application
Useful for studying protein binding and screening small molecular inhibitors
Endotoxin Level
<1 EU/ug
Notes
The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_022153
Mw(kda)
46.7 kDa
Synonyms
Platelet receptor Gi24 Dies1, VISTA, SISP1
Uniprot
Q9H7M9
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Byrum, J.N., et al., J. Immunol. 2013 Sep 15;191(6):3073-3081. 2. Zhu, Y., et al., Nat Commu. 2013;4:2043.