Human secreted B7-2, Fc fusion protein, also known as T-lymphocyte activation antigen CD86, B7.2, FUN-1, B70, BU63, and CD86. GenBank Accession No. NM_006889, a.a. 20-239 expressed in a HEK293 cell expression system. This protein is fused at the C-terminus to the Fc region of human IgG1 and is enzymatically biotinylated using Avi-tag technology. MW = 53.8 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Immunogen Region
20-239
Tag
C-terminal Fc fusion, C-terminal Avi-tag
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Species
Human
Application
Useful for studying protein binding and screening small molecular inhibitors
Notes
This protein runs ata higher MW by SDS-PAGE due toglycosylation. The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.