Human angiopoietin 2 (ANGPT2), also known as ANG-2, GenBank Accession No. NM_001147, a.a. 258-496 (end), with N-terminal FLAG-tag and mouse Cartilage Oligomeric Matrix Protein (COMP), GenBank Accession No. NM_016685, a.a. 28-72, MW=33.4 kDa, expressed in a HEK293 cell expression system.
Immunogen Region
ANG2 258-496 (end), COMP 28-72
Tag
N-terminal FLAG-tag
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.05% Tween-20, 100 ng/ul FLAG peptide, 20% glycerol, and 1 mM DTT.
Species
Human
Application
Useful for the study of signaling pathways. Also useful for receptor binding studies, screening inhibitors, and selectivity profiling.
Notes
Avoid freeze/thaw cycles.
GenBank
NM_001147 (ANG2), NM_016685 (COMP)
Mw(kda)
33.4 kDa
Synonyms
angiopoietin 2, ANGPT2, ANG-2
Uniprot
O15123
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Fiedler, U., et al., J. Biol Chem. 2003 Jan 17;278(3):1721-17. 2. Yuan, H.T., et al., Mol Cell Biol. 2009 Apr;29(8):2011-22.