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ALK , GST-tag

SKU : BHP18200195

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BPS Bioscience

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Mfr.No.	40214
Description	Human anaplastic lymphoma receptor tyrosine kinase (ALK), also known as CD246 and NBLST3, (GenBank Accession No. NM_004304), a.a. 1058-1620 (end) with N-terminal GST-tag, MW = 89 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Host cell line: Sf9 cells Specific activity: 77 pmol/min/ug.
Immunogen Region	1058-1620 (end)
Tag	N-terminal GST-tag
Formulation	40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, and 20% glycerol.
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	Assay was done in a Kinase buffer using 0.2 mg/ml IGF1Rtide as a substrate with 20 uM ATP at 30°C for 40 min. The amount of ATP transferred was calculated using Kinase-Glo reagent (Promega). Avoid freeze/thaw cycles.
GenBank	NM_004304
Mw(kda)	89 kDa

Synonyms	ALK, CD246, anaplastic lymphoma receptor tyrosine kinase, NBLST3
Uniprot	Q9UM73

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Ren, H., et al., Cancer Res. 2012,72(13):3312-3323. 2. Zhu, S., et al., Cancer Cell 2012,21(3):362-373. 3. Schonherr, C., et al., Crit Rev Oncog. 2012,17(2):123-143

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200195	40214	10 ug	$390.50		Add to Cart

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