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Home / Proteins & Peptide

Active Human Recombinant Gamma Synuclein Protein Pre-formed Fibrils (Type 1) BHP11901163

SKU : BHP11901163

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StressMarq Biosciences Inc.

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Mfr.No.	SPR-459, SPR-459B, SPR-459C, SPR-459E
Description	Active Human Recombinant Gamma Synuclein Protein Pre-formed Fibrils (Type 1)
Alternative Names	BCSG1 Aggregate Protein, Breast cancer specific gene 1 Aggregate Protein, Breast cancer specific Protein 1 Agreggates, Gamma-synuclein Aggregate Protein, Persyn Aggregate Protein, PRSN Aggregate Protein, SNCG Aggregate Protein, SR Aggregate Protein, Synoretin Aggregate Protein, Synuclein gamma Aggregate Protein, SYUG_HUMAN Aggregate Protein
Cellular Localization	Cytoskeleton, Centrosome, Spindle, Perinuclear Region
Certificate Of Analysis	Certified >95% pure using SDS-PAGE analysis.
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For research use only.
Scientific Background	Gamma synuclein is a neuronal protein found in peripheral and motor nerve systems. It has been implicated in the hippocampal axon pathology in Parkinson's Disease (1). A change in the expression of gamma synuclein has been observed in the retina of patients with Alzheimer's disease (2). Its expression in breast tumors is also a marker for tumor progression (3).
Species	Human
Accession Number	NP_003078.2
Concentration	Lot/batch specific. See included datasheet.
Purification	Ion-exchange Purified
Expression System	E. coli
Biological Activity Abreviation	Active
Cite This Product	Human Recombinant Gamma Synuclein Protein (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SPR-459E)
Mol Weight	13.33 kDa
Nature	Recombinant
Other Relevant Information	For best results, sonicate immediately prior to use. Refer to the Neurodegenerative Protein Handling Instructions on our website, or on the product datasheet for further information..
Protein Length	Full length

Gross Weight (kg)	1.4
Launch Date	03-18-2019
Net Weight (g)	0.5
Swissprot	O76070
Gene Id	6623
Research Area	Tangles & Tau, Neurodegeneration, Alzheimer's Disease, Parkinson's Disease, Synuclein, Neuroscience
Target	Gamma Synuclein

Country Of Origin	Canada
Stock Product	Y
Tarriff Code	3822.00.1090
Shipping Temperature	Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.
Purity	>95%
Storage Buffer	PBS pH 7.4
Storage Temperature	-80°C

Applications	In vivo assay, In vitro assay, WB, SDS-PAGE

Reference	1. Nemoto, T. et al. (1997) J.Biol Chem. 272: 26179-26187. 2. Minami, Y, et al. (1991), J.Biol Chem. 266: 10099-10103. 3. Arlander SJH, et al. (2003) J Biol Chem. 278: 52572-52577. 4. Pearl H, et al. (2001) Adv Protein Chem. 59: 157-186. 5. Neckers L, et al. (2002) Trends Mol Med. 8: S55-S61. 6. Pratt W, Toft D. (2003) Exp Biol Med. 228: 111-133. 7. Pratt W, Toft D. (1997) Endocr Rev. 18: 306- 360. 8. Pratt WB. (1998) Proc Soc Exptl Biol Med. 217: 420- 434. 9. Whitesell L, et al. (1994) Proc Natl Acad Sci USA. 91: 8324- 8328. 10. Nemoto, T. (1997) Biochem and Mol. Bio Intl. 42 (5): 881-889.

Product Manual	Datasheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP11901163-1	SPR-459B	100 ug	$505		Add to Cart
BHP11901163-2	SPR-459C	2X100 ug	$807		Add to Cart
BHP11901163-3	SPR-459E	5X100 ug	$1641		Add to Cart

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