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Home / Proteins & Peptide

Active Human Recombinant Beta Synuclein Protein Monomers BHP11901127

SKU : BHP11901127

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StressMarq Biosciences Inc.

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Mfr.No.	SPR-405, SPR-405B, SPR-405C, SPR-405E
Description	Active Human Recombinant Beta Synuclein Protein Monomers
Alternative Names	14 kDa brain-specific protein, Beta-synuclein Protein, Phosphoneuroprotein 14 Protein, PNP14 Protein, Sncb Protein, Synuclein beta Protein, SYUB_HUMAN Protein
Cellular Localization	Cytoplasm
Certificate Of Analysis	Certified >95% pure using SDS-PAGE analysis.
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For research use only.
Scientific Background	Alzheimer s Disease (AD) is the most common neurodegenerative disease, affecting 10% of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Beta synuclein is abundant in neurofibrillary lesions of patients with Alzheimer's Disease. Beta synuclein is suggested to be an inhibitor of alpha synuclein aggregation- protecting the central nervous system from the neurotoxin effects of alpha synuclein (3).
Species	Human
Accession Number	NP_001001502.1
Concentration	Lot/batch specific. See included datasheet.
Purification	Ion-exchange Purified
Expression System	E. coli
Biological Activity Abreviation	Active
Cite This Product	Human Recombinant Beta Synuclein Protein (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SPR-405E)
Mol Weight	14.28 kDa
Nature	Recombinant
Protein Length	Full length

Gross Weight (kg)	1.4
Launch Date	03-18-2019
Net Weight (g)	0.5
Swissprot	Q16143
Gene Id	6620
Research Area	Tangles & Tau, Neurodegeneration, Alzheimer's Disease, Parkinson's Disease, Synuclein, Neuroscience
Target	Beta Synuclein

Country Of Origin	Canada
Stock Product	Y
Tarriff Code	3822.00.1090
Shipping Temperature	Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.
Purity	>95%
Storage Buffer	PBS pH 7.4
Storage Temperature	-80°C

Applications	In vivo assay, In vitro assay, WB, SDS-PAGE

Reference	1. Nemoto T., et al. (1997) J.Biol Chem. 272: 26179-26187. 2. Minami Y., et al. (1991), J.Biol Chem. 266: 10099-10103. 3. Arlander S.J.H., et al. (2003) J Biol Chem 278: 52572-52577. 4. Pearl H., et al. (2001) Adv Protein Chem 59:157-186. 5. Neckers L., et al. (2002) Trends Mol Med 8:S55-S61. 6. Pratt W., Toft D. (2003) Exp Biol Med 228:111-133. 7. Pratt W., Toft D. (1997) Endocr Rev 18:306- 360. 8. Pratt W.B. (1998) Proc Soc Exptl Biol Med 217: 420- 434. 9. Whitesell L., et al. (1994) Proc Natl Acad Sci USA 91: 8324- 8328. 10. Barent R. L. (1998) Mol. Endocrinol. 12: 342-354 11. Lo. M.A. (1998) EMBO J. 17: 6879-6887.

Product Manual	Datasheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP11901127-1	SPR-405B	100 ug	$382		Add to Cart
BHP11901127-2	SPR-405C	2X100 ug	$611		Add to Cart
BHP11901127-3	SPR-405E	5X100 ug	$1240		Add to Cart

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