Recombinant human ACE2 (angiotensin converting enzyme 2), encompassing amino acids 18-740. The protein is fused in C-terminal with the Fc fragment of a human IgG1 followed by a C-terminal Avi-Tag. The recombinant protein was enzymatically biotinylated using the Avi-Tag and affinity purified. HiP indicates a high purity protein (>=90% pure) and less than 10% aggregation as measured by gel filtration. Constructs: ACE2 (18-740-Fc(lgG1)-Avi)-(Biotin)
Immunogen Region
18-740
Tag
C-terminal Fc-Avi-Tag
Formulation
8 mM phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl, 20% glycerol
Species
Human
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes
Assay was done according to the ACE2 Inhibitor Screening Kit (Biohippo #79923) with various amounts of ACE2.