Zika Virus Ns2B-Ns3 (S2) protein

Mfr.No.	0555-001
Description	The Zika Virus NS2B-NS3 (S2) protein is a highly purified recombinant protein designed for advanced virology research. This protein plays a critical role in viral replication, serving as a target for drug discovery and therapeutic interventions. It functions as a serine protease, facilitating the cleavage of viral polyproteins essential for replication and maturation. Expressed in Drosophila S2 cells using the ExpreS2™ system and purified via column chromatography, the NS2B-NS3 protease complex is a reliable resource for understanding Zika virus pathogenesis. Key Advantages High Purity: Greater than 95% as confirmed by SDS-PAGE and HPLC. Functional Integrity: Verified protease activity for reliable experimental outcomes with consistent performance in inhibitor screening assays. Ease of Use: Supplied in a ready-to-use liquid format in PBS. Flexible Applications: Suitable for structural studies, enzymatic assays, and drug discovery research. Reproducibility: Produced under stringent quality control to ensure batch-to-batch consistency. Endotoxin-Free: Guaranteed for sensitive applications.
Product Type	Other Viruses
Features	Origin: Recombinant Zika Virus NS2B-NS3 (S2) protein. Expression System: Drosophila S2 insect cells using ExpreS2™ technology, optimizing post-translational modifications. Purification: Multi-step column chromatography ensuring high purity and activity. Molecular Weight: 26.8 kDa (theoretical). Format: Liquid in phosphate-buffered saline (PBS). Storage: Store at -80°C for long-term stability; aliquot to avoid freeze-thaw cycles.
Quantity	Rigorous validation of purity and activity using SDS-PAGE, HPLC, and activity assays. Comprehensive testing to ensure endotoxin-free preparations (≤0.1 EU/µg protein). Batch-to-batch reproducibility verified with standardized protocols. Accompanied by a Certificate of Analysis for every lot, detailing purity, activity, and endotoxin levels
Application	Protease Activity Studies: The Zika virus NS2B-NS3 protease has been widely studied for its enzymatic mechanisms. For instance, NS2B-NS3 protease activity has been analyzed using fluorogenic and chromogenic substrates to better understand its catalytic properties and interactions (Xing et al.). Inhibitor Screening: High-throughput methods have identified promising small molecules and peptides that inhibit NS2B-NS3 activity. Notable studies highlight potential antiviral candidates and computational screening methods to design effective inhibitors (Hossain et al.; Nascimento et al.). Structural Biology: Structural studies, including crystallography and NMR, have resolved the protease's configuration and provided insights into the molecular basis of inhibitor binding, critical for drug design (Zhang et al.; Penna et al.). Viral Pathogenesis Research: NS2B-NS3 plays a vital role in Zika virus replication and interaction with host cellular machinery. Research has elucidated its dual functionality, offering insights into viral replication and pathogenesis (Shiryaev et al.). High-Throughput Screening: Assay platforms leveraging the NS2B-NS3 protease have been developed to facilitate drug discovery efforts. Such platforms have proven effective for rapid evaluation of antiviral compounds (Li et al.).
Purification	Column chromatography
Abbreviation	Zika Ns2B-Ns3 dimer (S2)
Notes	Support and Services Our team of scientific experts is available to provide technical support and guidance. Contact us for assistance in optimizing your experiments or for custom protein production services. Contact Us: For more information, reach out at [email protected]. Why Choose IBT Bioservices via eBioHippo? IBT Bioservices via eBioHippo is dedicated to empowering researchers with cutting-edge tools and solutions for life sciences. All our products are backed by rigorous quality control and expert support from our suppliers, ensuring your research achieves its highest potential.
Expression	S2 cells
Lead Time	Typical lead time is 1-2 weeks from order confirmation.

Target Details	Zika virus Ns2B-Ns3 dimer
Target Pathogen	Zika Virus

Shipping	1 week. Shipped on dry ice to ensure stability during transit.

Applications	WB

Have you used this product?

Rate it now..!!

SKU	Supplier No.	Size	Your price	Quantity
BHP20900036	0555-001	100 ug	$570.94		Add to Cart

Why Choose IBT Bioservices via eBioHippo?
IBT Bioservices via eBioHippo is dedicated to empowering researchers with cutting-edge tools and solutions for life sciences. All our products are backed by rigorous quality control and expert support from our suppliers, ensuring your research achieves its highest potential.
Frequently Asked Questions (FAQ)

Q: What makes the NS2B-NS3 protein from eBioHippo unique?
A: It is expressed using advanced ExpreS2™ technology, ensuring high purity, functional activity, and consistent quality.

Q: Can I request custom modifications?
A: Yes, custom tags, formulations, and activity assays are available upon request.

Q: How do you ensure batch-to-batch consistency?
A: Rigorous quality control measures, including activity assays and purity validation, are implemented for every production batch.

Q: Do you provide bulk order discounts?
A: Yes, please contact us for bulk pricing and customization options.

Q: What applications is this protein most suited for?
A: It is ideal for inhibitor screening, enzymatic activity assays, structural biology, and studying viral pathogenesis.

Zika Virus Ns2B-Ns3 (S2) protein

Contact us to order

Tel

Email

Contact us to order

Tel

Email

Reviews of Zika Virus Ns2B-Ns3 (S2) protein

Rate it now..!!