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Home / Antibodies

Protein PML Antibody (RQ6506)

SKU : BHA17122767

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NSJ Bioreagents

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Mfr.No.	RQ6506
Clonality	Polyclonal (rabbit origin)
Description	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An E. coli-derived mouse protein (amino acids E107-A857) was used as the immunogen for the Protein PML antibody.
Isotype	Rabbit IgG
Species Reactivity	Mouse, Rat
Note	Optimal dilution of the Protein PML antibody should be determined by the researcher.

Uniprot	Q60953

Format	Antigen affinity purified
Purity	Affinity purified
Storage	After reconstitution, the Protein PML antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	WB, IHC-P, FACS, Direct ELISA
Description	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17122767	RQ6506	100ug	$419		Add to Cart

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