Transcription repressor that specifically binds to the 5'-TATTTT(T/G)-3' consensus sequence on promoters and repress transcription of PGC-1-alpha(PPARGC1A), thereby playing a role in regulation of neuron death.
Clonality
polyclonal
Host
Rabbit
Immunogen
zinc finger protein 746
Immunogen Region
zinc finger protein 746
Isotype
IgG
Molecular Weight
50-55kDa,70-85 kDa
Reactivity
Human, Rat
Recommended Dilution
WB: 1:500-1:5000; IHC: 1:20-1:200
Subcellular Location
Cytoplasm, Nucleus
Synonyms
FLJ31413, zinc finger protein 746, ZNF746
Uniprot
Q6NUN9
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:5000; IHC: 1:20-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10734.pdf" target="_blank">Data Sheet</ a>