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Home / Primary Antibodies / Promotion

YWHAB antibody

SKU : BHA10809546

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Mfr.No.	FNab09575
Alternative Names	1433 ; 1433alpha ; 1433proteinbeta/alpha ; YWHAB
Background	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form(by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm
Clonality	polyclonal
Description	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13.
Host	Rabbit
Immunogen	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
Isotype	IgG
Molecular Weight	28 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cytoplasm
Synonyms	14 3 3, 14 3 3 alpha, 14 3 3 protein beta/alpha, YWHAB

Uniprot	P31946
Gene Id	7529
Research Area	Signal Transduction, Metabolism, Neuroscience
Weight	28kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC

Description

ELISA ; IHC

Dilution

IHC	1:20-1:200

Tested Application

IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809546	FNab09575	100ug	$300		Add to Cart

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