This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patteing during embryogenesis. Alteatively spliced transcript variants have been identified for this gene.
Categories
Primary Antibodies
Cellular Localization
Extracellular matrix, Secreted
Clonality
polyclonal
Description
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
Host
Rabbit
Immunogen
wingless-type MMTV integration site family member 2
Isotype
IgG
Molecular Weight
50 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Extracellular matrix, Secreted
Synonyms
WNT2, Protein Wnt 2, INT1L1, IRP, Int 1 like protein 1
Uniprot
P09544
Gene Id
7472
Research Area
Developmental biology, Cardiovascular, Signal Transduction
Weight
40kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)