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Home / Primary Antibodies / Promotion

USP9X antibody

SKU : BHA10809325

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Mfr.No.	FNab09344
Alternative Names	DeubiquitinatingenzymeFAFX ; DFFRX ; FAF ; FAM ; Fatfacetsinmammals ; hFAM ; UbiquitinthiolesteraseFAFX ; USP9 ; USP9X
Background	Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein tuover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'-and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration.
Categories	Primary Antibodies
Cellular Localization	Cell Projection, Cytoplasm
Clonality	polyclonal
Description	Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein tuover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration.
Host	Rabbit
Immunogen	ubiquitin specific peptidase 9, X-linked
Isotype	IgG
Molecular Weight	260-290 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cell projection, Cytoplasm
Synonyms	Deubiquitinating enzyme FAF X, DFFRX, FAF, FAM, Fat facets in mammals, hFAM, Ubiquitin thiolesterase FAF X, USP9, USP9X

Uniprot	Q93008
Gene Id	8239
Research Area	Epigenetics, Cell Division and Proliferation, Developmental biology, Metabolism
Weight	292kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IF, IHC, IP

Description

ELISA ; WB ; IF ; IHC ; IP

Dilution

WB	1:500-1:5000
IF	1:10-1:100
IHC	1:20-1:200
IP	1:200-1:2000

Tested Application

WB: 1:500-1:5000; IF: 1:10-1:100; IHC: 1?20-1?200; IP: 1?200-1?2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809325	FNab09344	100ug	$300		Add to Cart

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