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Home / Primary Antibodies / Polyclonal Antibodies

USP25 antibody

SKU : BHA10809304

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Mfr.No.	FNab09321
Alternative Names	Deubiquitinatingenzyme25 ; Ubiquitinthiolesterase25 ; USPonchromosome21 ; USP21 ; USP25
Background	Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999 (PubMed 10644437)).
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, Nucleus
Clonality	polyclonal
Description	Deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. Hydrolyzes both 'Lys-48'- and 'Lys-63'-linked tetraubiquitin chains. The muscle-specific isoform (USP25m) may have a role in the regulation of muscular differentiation and function.
Host	Rabbit
Immunogen	ubiquitin specific peptidase 25
Isotype	IgG
Molecular Weight	130 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cytoplasm, Nucleus
Synonyms	Deubiquitinating enzyme 25, Ubiquitin thiolesterase 25, USP on chromosome 21, USP21, USP25

Uniprot	Q9UHP3
Gene Id	29761
Research Area	Epigenetics, Metabolism
Weight	125kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:200-1:2000

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab09321.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809304	FNab09321	100ug	$300		Add to Cart

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