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Home / Primary Antibodies / Polyclonal Antibodies

USP1 antibody

SKU : BHA10809287

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Mfr.No.	FNab09302
Alternative Names	Deubiquitinatingenzyme1 ; hUBP ; ubiquitinspecificpeptidase1 ; Ubiquitinthiolesterase1 ; UBP ; USP1
Background	Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).
Categories	Primary Antibodies
Cellular Localization	Nucleus
Clonality	polyclonal
Description	Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2 (PubMed:15694335). Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA (PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:18082604, PubMed:26388029).
Host	Rabbit
Immunogen	ubiquitin specific peptidase 1
Isotype	IgG
Molecular Weight	100 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Nucleus
Synonyms	Deubiquitinating enzyme 1, hUBP, ubiquitin specific peptidase 1, Ubiquitin thiolesterase 1, UBP, USP1

Uniprot	O94782
Gene Id	7398
Research Area	Epigenetics, Metabolism
Weight	88kDa,Observed 88kDa，100kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IP

Description

ELISA ; WB ; IHC ; IP

Dilution

WB	1:200-1:2000
IHC	1:20-1:200
IP	1:200-1:1000

Tested Application

WB: 1:200-1:2000; IHC: 1:20-1:200?IP: 1:200-1:1000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809287	FNab09302	100ug	$300		Add to Cart

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