This antibody can recognize all the four members of UBE2D due to the high homology.
Categories
Primary Antibodies
Cellular Localization
Cytoplasm
Clonality
polyclonal
Description
UBE2D1(Ubiquitin-conjugating enzyme E2 D1) is also named as SFT, UBC5A, UBCH5, UBCH5A and belongs to the ubiquitin-conjugating enzyme family. It regulates DAPK3 accumulation in promyelocytic leukemia protein nuclear body (PML-NB)by interacting with DAPK3 and stimulating its ubiquitination. It is a promiscuous E2 enzyme with an innate preference for forming polyubiquitin chains through lysine 11 (K11), lysine 48 (K48), and lysine 63 (K63) of ubiquitin(PMID:21396940). This antibody is specific to UBE2D1.
Host
Rabbit
Immunogen
ubiquitin-conjugating enzyme E2D 1
Isotype
IgG
Molecular Weight
14 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Cytoplasm
Synonyms
E2(17)KB1, SFT, Stimulator of Fe transport, UBC4/5, UBC4/5 homolog, UBC5A, UBCH5, UBCH5A, UBE2D1, Ubiquitin carrier protein D1, Ubiquitin protein ligase D1
Uniprot
P51668
Gene Id
7321
Research Area
Epigenetics, Metabolism
Weight
17kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)