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Home / Primary Antibodies / Promotion

UBA6 antibody

SKU : BHA10809138

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Mfr.No.	FNab09146
Alternative Names	E1L2 ; FLJ10808 ; FLJ23367 ; Monocyteprotein4 ; MOP4 ; MOP4 ; UBA6 ; UBE1L2 ; Ubiquitinactivatingenzyme6
Background	Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 (PubMed 17597759)).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin- E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility.
Host	Rabbit
Immunogen	ubiquitin-like modifier activating enzyme 6
Isotype	IgG
Molecular Weight	59 kDa, 118 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	E1 L2, FLJ10808, FLJ23367, Monocyte protein 4, MOP 4, MOP4, UBA6, UBE1L2, Ubiquitin activating enzyme 6

Uniprot	A0AVT1
Gene Id	55236
Research Area	Epigenetics, Metabolism
Weight	118kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:200-1:2000

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab09146.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809138	FNab09146	100ug	$300		Add to Cart

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