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Home / Primary Antibodies / Polyclonal Antibodies

UAP56 antibody

SKU : BHA10809134

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Mfr.No.	FNab09142
Alternative Names	ATPdependentRNAhelicasep47 ; BAT1 ; D6S81E ; DDX39B ; DEADboxproteinUAP56 ; HLABassociatedtranscript1 ; SpliceosomeRNAhelicaseBAT1 ; UAP56
Background	This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alteative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2) gene.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, Nucleus, Spliceosome
Clonality	polyclonal
Description	BAT1, aslo named as DDX39B or UAP56, is a 428 amino acid protein, which contains one helicase C-terminal domain, one helicase ATP-binding domain and belongs to the DEAD box helicase family. DECD subfamily. BAT1 localizes in the nucleus and cytoplasm. BAT1 is involved in nuclear export of spliced and unspliced mRNA. BAT1 as ATP dependent RNA helicase, may be a translation initiation factor and acts as a negative regulator of inflammatory cytokines.
Host	Rabbit
Immunogen	HLA-B associated transcript 1
Isotype	IgG
Molecular Weight	49 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Subcellular Location	Cytoplasm, Nucleus, Spliceosome
Synonyms	ATP dependent RNA helicase p47, BAT1, D6S81E, DDX39B, DEAD box protein UAP56, HLA B associated transcript 1, Spliceosome RNA helicase BAT1, UAP56

Uniprot	Q13838
Gene Id	7919
Research Area	Epigenetics
Weight	50kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IP

Description

ELISA ; WB ; IHC ; IP

Dilution

WB	1:500-1:5000
IP	1:200-1:2000
IHC	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

Manual	FNab09142.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809134	FNab09142	100ug	$300		Add to Cart

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