Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity(via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.
Host
Rabbit
Immunogen
TTK protein kinase
Isotype
IgG
Molecular Weight
97 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
ESK, FLJ38280, MPS1, MPS1L1, PYT, TTK, TTK protein kinase
Uniprot
P33981
Gene Id
7272
Research Area
Cell Division and Proliferation, Metabolism
Weight
97kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)