Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock.
Clonality
polyclonal
Host
Rabbit
Immunogen
triggering receptor expressed on myeloid cells 1
Immunogen Region
triggering receptor eXpressed on myeloid cells 1
Isotype
IgG
Molecular Weight
25-30 kDa
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Synonyms
CD354,TREM-1,Triggering receptor expressed on monocytes 1
Uniprot
Q9NP99
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000; IHC: 1:20-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10738.pdf" target="_blank">Data Sheet</ a>