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Home / Primary Antibodies / Polyclonal Antibodies

Trefoil factor 1 antibody

SKU : BHA10808950

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Mfr.No.	FNab08958
Alternative Names	D21S21 ; HP1.A ; HPS2 ; pNR2 ; PolypeptideP1.A ; ProteinpS2 ; pS2 ; TFF1 ; trefoilfactor1
Background	Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
Categories	Primary Antibodies
Clonality	polyclonal
Description	TFF1 (formerly known as pS2) is a small-secreted protein that belongs to the family of trefoil peptides, and characterized by the presence of one to six cysteine-rich P domains. TFF1 expression is frequently lost in gastric carcinoma, probably through mechanism of DNA methylation, and it is therefore considered as a tumor suppressor gene. The function of TFF1 was first controversially considered as an oncogene in breast cancer.
Host	Rabbit
Immunogen	trefoil factor 1
Isotype	IgG
Molecular Weight	12 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	D21S21, HP1.A, HPS2, pNR 2, Polypeptide P1.A, Protein pS2, pS2, TFF1, trefoil factor 1

Uniprot	P04155
Gene Id	7031
Research Area	Cancer, Metabolism
Weight	9kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF

Dilution

WB	1:200-1:2000
IHC	1:20-1:200
IF	1:20-1:200

Tested Application

WB: 1:500 - 1:1000; IHC: 1:50 - 1:200

Manual	FNab08958.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808950	FNab08958	100ug	$300		Add to Cart

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