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Home / Primary Antibodies / Polyclonal Antibodies

TPM2 antibody

SKU : BHA10808881

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Mfr.No.	FNab08889
Alternative Names	TMSB
Background	This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alteatively spliced transcript variants encoding different isoforms have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor intealization (By similarity).
Host	Rabbit
Immunogen	tropomyosin 2 (beta)
Isotype	IgG
Molecular Weight	36 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	TMSB

Uniprot	P07951
Gene Id	7169
Research Area	Developmental biology, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF, IP
Description	ELISA ; WB ; IHC ; IF ; IP
Tested Application	WB: 1:500 - 1:1000; IHC: 1:50 - 1:100

Manual	FNab08889.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808881	FNab08889	100ug	$300		Add to Cart

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