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Home / Primary Antibodies / Polyclonal Antibodies

TNNC1 antibody

SKU : BHA10808827

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Mfr.No.	FNab08835
Alternative Names	TNNC
Background	Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
Host	Rabbit
Immunogen	troponin C type 1 (slow)
Isotype	IgG
Molecular Weight	18 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	TNNC

Uniprot	P63316
Gene Id	7134
Research Area	Developmental biology, Cardiovascular, Signal Transduction, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab08835.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808827	FNab08835	100ug	$300		Add to Cart

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