Organelle-specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. Forms a potassium-permeable leak-like channel, which regulates lumenal pH stability and is required for autophagosome-lysosome fusion. Constitutes the major lysosomal potassium channel.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Organelle-specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. Forms a potassium-permeable leak-like channel, which regulates lumenal pH stability and is required for autophagosome-lysosome fusion. Constitutes the major lysosomal potassium channel.
Host
Rabbit
Immunogen
transmembrane protein 175
Isotype
IgG
Molecular Weight
54-60 kDa, 41-45 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
TMEM175, transmembrane protein 175
Uniprot
Q9BSA9
Gene Id
84286
Research Area
Cell Division and Proliferation
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)