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Home / Primary Antibodies / Polyclonal Antibodies

Tie2 antibody

SKU : BHA10808682

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Mfr.No.	FNab08690
Background	This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alteative splicing results in multiple transcript variants. Additional alteatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	TEK tyrosine kinase, endothelial
Isotype	IgG
Molecular Weight	126kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CD202B, GLC3E, TIE-2, TIE2, VMCM, VMCM1

Uniprot	Q02763
Gene Id	7010
Research Area	Developmental biology, Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IP
Description	ELISA ; WB ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Manual	FNab08690.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808682	FNab08690	100ug	$300		Add to Cart

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