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Home / Primary Antibodies / Polyclonal Antibodies

TEAD3 antibody

SKU : BHA10808575

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Mfr.No.	FNab08583
Alternative Names	TEAD5 ; TEF5
Background	This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is predominantly expressed in the placenta and is involved in the transactivation of the chorionic somatomammotropin-B gene enhancer. Translation of this protein is initiated at a non-AUG (AUA) start codon.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in tu phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.
Host	Rabbit
Immunogen	TEA domain family member 3
Isotype	IgG
Molecular Weight	49 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	TEAD5, TEF5

Uniprot	Q99594
Gene Id	7005
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab08583.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808575	FNab08583	100ug	$300		Add to Cart

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