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Home / Primary Antibodies / Polyclonal Antibodies

SPIN1 antibody

SKU : BHA10808169

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Mfr.No.	FNab08177
Alternative Names	OCR ; SPIN
Categories	Primary Antibodies
Clonality	polyclonal
Description	Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway downstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006). May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating mateal transcripts to control meiotic resumption.
Host	Rabbit
Immunogen	spindlin 1
Isotype	IgG
Molecular Weight	32 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	OCR, SPIN

Uniprot	Q9Y657
Gene Id	10927
Research Area	Developmental biology

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IP, IHC
Description	ELISA ; WB ; IP ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab08177.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808169	FNab08177	100ug	$300		Add to Cart

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