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Home / Primary Antibodies / Promotion

SPHK1 antibody

SKU : BHA10808165

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Mfr.No.	FNab08173
Alternative Names	SPHK ; SPK
Background	The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alteatively spliced transcript variants encoding different isoforms have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.
Host	Rabbit
Immunogen	sphingosine kinase 1
Isotype	IgG
Molecular Weight	55 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	SPHK, SPK

Uniprot	Q9NYA1
Gene Id	8877
Research Area	Cardiovascular, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC
Description	ELISA ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab08173.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808165	FNab08173	100ug	$300		Add to Cart

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