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Home / Primary Antibodies / Promotion

SOST antibody

SKU : BHA10808111

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Mfr.No.	FNab08119
Alternative Names	sclerosteosis ; Sclerostin ; SOST ; VBCH
Background	Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Host	Rabbit
Immunogen	sclerosteosis
Isotype	IgG
Molecular Weight	30 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	sclerosteosis, Sclerostin, SOST, VBCH

Uniprot	Q9BQB4
Gene Id	50964
Research Area	Signal Transduction, Metabolism, Immunology, Cancer, Stem Cells
Weight	24 kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Manual	FNab08119.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808111	FNab08119	100ug	$300		Add to Cart

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