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Home / Primary Antibodies / Polyclonal Antibodies

SIN3A antibody

SKU : BHA10807862

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Mfr.No.	FNab07870
Background	The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation.
Host	Rabbit
Immunogen	SIN3 homolog A, transcription regulator (yeast)
Isotype	IgG
Molecular Weight	147 kDa
Reactivity	Human, Rat
Regulatory	RUO

Uniprot	Q96ST3
Gene Id	25942
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF, IP
Description	ELISA ; WB ; IF ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab07870.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807862	FNab07870	100ug	$300		Add to Cart

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