This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alteatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.
Host
Rabbit
Immunogen
RUN and FYVE domain containing 1
Isotype
IgG
Molecular Weight
80 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
RABIP4, ZFYVE12
Uniprot
Q96T51
Gene Id
80230
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)