This gene encodes a protein that associates with the nuclear pore complex and participates in the regulation of nuclear transport. The encoded protein interacts with Ras-related nuclear protein 1 (RAN) and regulates guanosine triphosphate (GTP)-binding and exchange. Alteative splicing results in multiple transcript variants.
Categories
Primary Antibodies
Clonality
polyclonal
Description
GTPase activator for the nuclear Ras-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state.
Host
Rabbit
Immunogen
Ran GTPase activating protein 1
Isotype
IgG
Molecular Weight
64 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
KIAA1835, SD
Uniprot
P46060
Gene Id
5905
Research Area
Cell Division and Proliferation, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)