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Home / Primary Antibodies / Promotion

RAC2 antibody

SKU : BHA10807059

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Mfr.No.	FNab07067
Background	This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
Host	Rabbit
Immunogen	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
Isotype	IgG
Molecular Weight	21 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Uniprot	P15153
Gene Id	5880
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IP
Description	ELISA ; WB ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab07067.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10807059	FNab07067	100ug	$300		Add to Cart

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