Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alteates between a GTP-bound active form and a GDP-bound inactive form.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alteates between a GTP-bound active form and a GDP-bound inactive form.
Host
Rabbit
Immunogen
RAB22A, member RAS oncogene family
Isotype
IgG
Molecular Weight
22 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
RAB22
Uniprot
Q9UL26
Gene Id
57403
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)