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Home / Primary Antibodies / Polyclonal Antibodies

PTP4A3 antibody

SKU : BHA10806921

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Mfr.No.	FNab06929
Alternative Names	PRL3 ; PRLR ; PRL3 ; PTP4A3
Background	This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alteative splicing results in multiple transcript variants.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.
Host	Rabbit
Immunogen	protein tyrosine phosphatase type IVA, member 3
Isotype	IgG
Molecular Weight	15 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	PRL 3, PRL R, PRL3, PTP4A3

Uniprot	O75365
Gene Id	11156
Research Area	Developmental biology, Metabolism
Weight	20kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC, WB

Description

ELISA ; IHC ; WB

Dilution

WB	1:200-1:2000
IHC	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Manual	FNab06929.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806921	FNab06929	100ug	$300		Add to Cart

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