This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alteative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alteatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur.
Clonality
polyclonal
Host
Rabbit
Immunogen
PCDH15
Immunogen Region
PCDH15
Isotype
IgG
Molecular Weight
100kDa
Reactivity
Human, Rat
Recommended Dilution
IHC: 1:20-1:200
Synonyms
CDHR15, DFNB23, USH1F, PCD15
Uniprot
Q96QU1
Gene Id
65217
Research Area
Metabolism
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
IHC: 1:20-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10098.pdf" target="_blank">Data Sheet</ a>