Dock4 is a member of the dedicator of cytokinesis(DOCK) family and encodes a protein with a DHR-1(CZH-1) domain, a DHR-2(CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
bone gamma-carboxyglutamate(gla) protein
Isotype
IgG
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
BGLAP, Osteocalcin, BGP, Bone Gla protein, OC, OCN, Osteocalcin, PMF1
Uniprot
P02818
Gene Id
632
Research Area
Developmental biology, Stem Cells, Immunology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)